Functional genomics studies of Rhipicephalus (Boophilus) annulatus ticks in response to infection with the cattle protozoan parasite, Babesia bigemina

► Genes differentially expressed in Babesia bigemina-infected Rhipicephalus annulatus were identified. ► Functional analyses were conducted using RNA interference. ► Rhipicephalus annulatus genes found will contribute to the development of novel vaccines.