Facile synthesis of magnetic one-dimensional polyaniline and its application in magnetic solid phase extraction for fluoroquinolones in honey samples

In this work, we proposed a simple co-mixing method to fabricate magnetic one-dimensional polyaniline (denoted as 1D-PANIs/MNPs). One-dimensional polyanilines (1D-PANIs) and magnetic nanoparticles (MNPs) were prepared by chemical oxidation and solvothermal methods, respectively. When MNPs and 1D-PANIs (with mass ratio 4:1) were co-mixed and vortexed evenly in a solvent (e.g., ethanol, water, acetonitrile), they could assemble into 1D-PANIs/MNPs spontaneously and thus be magnetically separable. To testify the feasibility of 1D-PANIs/MNPs in sample preparation, it was applied as the sorbent for magnetic solid phase extraction (MSPE) of fluoroquinolones (FQs) in honey samples. Under optimized conditions, a rapid, convenient, and efficient method for the determination of four FQs in honey samples by 1D-PANIs/MNPs-based MSPE coupling with high performance liquid chromatography with fluorescence detection (HPLC-FLD) was established. The limits of detection (LODs) for four FQs ranged from 0.4 to 1.4 ng g−1. The intra- and interday relative standard deviations (RSDs) were less than 17.6%. The recoveries of FQs for three spiked honey samples ranged from 86.3 to 121.3%, with RSDs of less than 16.3%.

By mixing magnetic nanoparticles (MNPs) and one-dimensional polyanilines (1D-PANIs) in a solvent, magnetic one-dimensional polyanilines (1D-PANIs/MNPs) were formed facilely due to the encapsulation of magnetic nanoparticles into the interconnected network of 1D-PANIs. The 1D-PANIs/MNPs have been demonstrated to be applicable for magnetic solid-phase extraction.Figure optionsDownload as PowerPoint slideHighlights
► Magnetic 1D polyaniline (1D-PANIs/MNPs) was prepared by a simple co-mixing method.
► Efficacy of 1D-PANIs/MNPs for isolating four fluoroquinolones (FQs) from honey was tested.
► The optimized conditions were established for 1D-PANIs/MNPs-based magnetic solid-phase extraction (MSPE).
► π–π and hydrophobic interactions played a dominant role to the retention between the FQs and 1D-PANIs/MNPs.
► A simple, rapid, and effective MSPE-HPLC analysis method for FQs in honey samples was developed.