Potentiometric flow injection system for determination of reductants using a polymeric membrane permanganate ion-selective electrode based on current-controlled reagent delivery

A polymeric membrane permanganate-selective electrode has been developed as a current-controlled reagent release system for potentiometric detection of reductants in flow injection analysis. By applying an external current, diffusion of permanganate ions across the polymeric membrane can be controlled precisely. The permanganate ions released at the sample-membrane interface from the inner filling solution of the electrode are consumed by reaction with a reductant in the sample solution thus changing the measured membrane potential, by which the reductant can be sensed potentiometrically. Ascorbate, dopamine and norepinephrine have been employed as the model reductants. Under the optimized conditions, the potential peak heights are proportional to the reductant concentrations in the ranges of 1.0 × 10−5 to 2.5 × 10−7 M for ascorbate, of 1.0 × 10−5 to 5.0 × 10−7 M for dopamine, and of 1.0 × 10−5 to 5.0 × 10−7 M for norepinephrine, respectively with the corresponding detection limits of 7.8 × 10−8, 1.0 × 10−7 and 1.0 × 10−7 M. The proposed system has been successfully applied to the determination of reductants in pharmaceutical preparations and vegetables, and the results agree well with those of iodimetric analysis.

A polymeric membrane permanganate-selective electrode has been developed as a current-controlled reagent release system for potentiometric detection of reductants in flow injection analysis. By applying an external current, diffusion of permanganate ions across the polymeric membrane can be controlled precisely. The permanganate ions released at the sample-membrane interface from the inner filling solution of the electrode are consumed by reaction with a reductant in the sample solution thus changing the measured membrane potential, by which the reductant can be sensed potentiometrically.Figure optionsDownload as PowerPoint slideHighlights
► A novel reagentless sensor is developed for consecutive detection of reductants in FIA.
► The ion-selective electrode is used as a permanganate controlled-release system.
► The amount of permanganate released at the membrane surface can be controlled precisely by an external current.
► The recovery of the sensor is rapid.