Development of a sensitive and selective Riboflavin sensor based on carbon ionic liquid electrode

The electrochemical properties of Riboflavin adsorbed on carbon ionic liquid electrode (CILE) were studied by cyclic voltammetry. A film with a surface coverage of up to 3.3 × 10−9 mol cm−2 was formed after 10 min exposure time. Electron transfer coefficient and rate constant of electron transfer across the modified electrode were found to be 0.43 and 3.03 s−1, respectively. Differential pulse voltammetry was used for the determination of Riboflavin. Two linear working ranges of 0.8–110 nM and 0.11–1.0 μM were obtained with correlation coefficients of 0.998 and 0.996, respectively. The experimental detection limit was obtained as 0.1 nM. The relative standard deviation for five replicate analyses was 4.7%. Other soluble vitamins had no significant interferences and the electrode was used for the determination of Riboflavin in pharmaceutical products, nutrition and beverages.