A versatile cryo-focussing flow switching gas chromatography inlet for trace analysis of intractable compounds

► Build a versatile GC inlet for traces of intractable compounds in complex mixtures. ► The inlet preserves the resolution and sensitivity of capillary GC analysis. ► The inlet delivers perfect peak shapes for acids, diols, bases in sub-nanogram amounts. ► The inlet provides LODs down to 0.09 ng, and LOQs robustly below 0.1-0.2 ng.