کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1218198 | 1494506 | 2014 | 8 صفحه PDF | دانلود رایگان |
• Phytochemical composition of bran samples from ten Maryland winter wheat varieties.
• Extracts assayed for total phenolics and antioxidant and antiproliferative activities.
• Ferulic acid was the predominant phenolic acid.
• Lutein, zeaxanthin, and β-carotene concentration were determined.
• α-Tocopherol and δ-tocopherol contents were quantified.
Phytochemicals (ferulic acid, tocopherols, and carotenoids) composition and antiproliferative activities of bran samples of the 10 soft winter wheat varieties grown in Maryland were investigated. All extracts were assayed for total phenolic content and free radical scavenging capacities by multiple colorimetric assays along with cellular antioxidant activity (CAA) and antiproliferative activity. Ferulic acid was the predominant phenolic acid in all 10 wheat bran samples with concentration ranging between 1.1 and 1.7 mg/g. The concentrations of lutein, zeaxanthin, and β-carotene ranged between 1.0–1.4, 0.2–0.3, and 0.1–0.2 μg/g, respectively. Significant amount of α-tocopherol (2.3–5.3 μg/g) was quantified in all bran samples along with minor quantity of δ-tocopherol (∼0.1 μg/g). No significant correlation between ferulic acid, tocopherol and carotenoid content and in vitro antioxidant radical scavenging assays or total phenolic content was observed. The Jamestown wheat bran demonstrated significant antiproliferative activities against both HT-29 and Caco-2 colon cancer cells at concentration of 50 mg bran equivalent (BE)/mL.
Journal: Journal of Food Composition and Analysis - Volume 36, Issues 1–2, November–December 2014, Pages 51–58