کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1244928 969707 2009 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Determination of ultra trace amount of enrofloxacin by adsorptive cathodic stripping voltammetry using copper(II) as an intermediate
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Determination of ultra trace amount of enrofloxacin by adsorptive cathodic stripping voltammetry using copper(II) as an intermediate
چکیده انگلیسی

In this work, a simple and sensitive electroanalytical method was developed for the determination of enrofloxacin (ENRO) by adsorptive cathodic stripping voltammetry (ADSV) using Cu(II) as a suitable probe. The complex of copper(II) with ENRO was accumulated at the surface of a hanging mercury drop electrode at −0.10 V for 40 s. Then, the preconcentrated complex was reduced and the peak current was measured using square wave voltammetry (SWV). The optimization of experimental variables was conducted by experimental design and support vector machine (SVM) modeling. The model was used to find optimized values for the factors such as pH, Cu(II) concentration and accumulation potential. Under the optimized conditions, the peak current at −0.30 V is proportional to the concentration of ENRO over the range of 10.0–80.0 nmol L−1 with a detection limit of 0.33 nmol L−1. The influence of potential interfering substances on the determination of ENRO was examined. The method was successfully applied to determination of ENRO in plasma and pharmaceutical samples.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Talanta - Volume 78, Issue 3, 15 May 2009, Pages 942–948
نویسندگان
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