Capillary-based immunoassays, immunosensors and DNA sensors – steps towards integration and multi-analysis

This review deals with immunoassays, immunosensors and DNA sensors based on capillaries. The one-dimensional cylindrical geometry of capillaries offers several advantages over other types of solid supports. Capillary assays are fast, sensitive and easy to automate. The small capillary dimensions permit low consumption of reagents and samples, while capillary walls can act as light waveguides and fluid cells. We review detection schemes developed for capillary-based single-analyte and multi-analyte binding assays and sensors.