Platinum complexes of terpyridine: Interaction and reactivity with biomolecules

Research on the coordination chemistry of Pt(II) terpyridine complexes spans more than 75 years, with significant recent work exploring the bioinorganic and medicinal chemistry of this diverse and versatile family of coordination compounds. This paper reviews the research literature describing investigations of the interactions of Pt(II) terpyridine complexes with nucleic acids and proteins.