کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1323311 | 1499929 | 2012 | 7 صفحه PDF | دانلود رایگان |
2-Mesitylindenyl phosphine ligand (1) and [(2-mesitylindenyl)dicyclohexyl-phosphine]PdCl2 (2) have been synthesized and fully characterized by NMR and elemental analysis, as well as by X-ray crystallography for 2. A Highly active catalyst system derived from a palladium precatalyst and bulky 2-mesitylindenyl phosphine ligand (1) for the Buchwald–Hartwig amination reaction of aryl halides with primary and secondary amines has been developed. This method allows for the preparation of a wide variety of amines in moderate to excellent yields and displays a high level of activity for the coupling of aryl chlorides as well as hindered aryl bromides.
2-Mesitylindenyl phosphine ligand and [(2-mesitylindenyl)dicyclohexyl phosphine]-PdCl2 have been synthesized, and utilized in the palladium-catalyzed Buchwald–Hartwig amination reaction, providing good to excellent yields of amination products. Figure optionsDownload as PowerPoint slideHighlights
► 2-Mesitylindenyl phosphine ligand (1) has been synthesized.
► [(2-Mesitylindenyl)dicyclohexyl-phosphine]PdCl2 (2) has been synthesized.
► A highly active catalyst system for the C–N coupling reaction has been developed.
Journal: Journal of Organometallic Chemistry - Volumes 706–707, 1 June 2012, Pages 99–105