Microwave promoted Suzuki reactions between aroyl chlorides and boronic acids catalyzed by heterogeneous and homogeneous phosphine-free palladium catalysts

Suzuki cross-coupling reactions between arylboronic acids and aroyl chlorides with phosphine-free palladium catalysis under microwave irradiation were performed to obtainment of aromatic ketones in good yields within short times. Heterogeneous and homogeneous catalysts were studied as well as their influence in the reaction selectivity relative to homocoupling of the boronic acids.

Suzuki cross-coupling reactions between arylboronic acids and aroyl chlorides with phosphine-free palladium catalysis under microwave irradiation were performed to obtainment of aromatic ketones in good yields within short times. Heterogeneous and homogeneous catalysts were studied as well as their influence in the reaction selectivity relative to homocoupling of the boronic acids.Figure optionsDownload as PowerPoint slideHighlights
► Applications in phosphine-free Pd-catalyzed cross-coupling reactions.
► Operationally simplistic and convenient synthetic route to aromatic ketones.
► Supported palladium catalysts, as well as Pd2dba3, has been found to be effective catalysts for the coupling of arylboronic acids with aroyl chlorides.