Homochiral porous metal-organic frameworks: Why and how?

This paper highlights the most significant recent advances in the synthesis, characterization, and applications of single-crystalline homochiral porous metal-organic frameworks (MOFs). The motivations for the synthesis of homochiral porous solids and the strategies on how they can be designed are provided. The latest examples of chiral separation and Lewis acid heterogeneous asymmetric catalysis using homochiral porous MOFs are presented.

A schematic representation of the active (BINOLate)Ti(OiPr)2 catalytic sites inside the open channels of a homochiral porous MOF.Figure optionsDownload as PowerPoint slide