Amorphous and nanostructured silica and aluminosilicate spray-dried microspheres

► The study is focused on development of nanocrystals on amorphous microspheres. ► The nanostructure is significant to biomedical applications. ► The nucleation induced by heat treatment starts on particle surface. ► The microspheres break down when they become highly crystalline. ► First NMR studies on spray dried aluminosilicate microspheres.