کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
14204 | 1188 | 2016 | 22 صفحه PDF | دانلود رایگان |
• Explains the operation principles of photonic hydrogel sensors
• Discusses holographic gratings, opals, porous silicons, block copolymers, Bragg stacks, and plasmonic composites
• Provides an overview of self-assembly and nano/microfabrication techniques
• Demonstrates clinical applications in point-of-care diagnostics
• Describes perceived limitations in sensing and provides guidelines for future work
Analyte-sensitive hydrogels that incorporate optical structures have emerged as sensing platforms for point-of-care diagnostics. The optical properties of the hydrogel sensors can be rationally designed and fabricated through self-assembly, microfabrication or laser writing. The advantages of photonic hydrogel sensors over conventional assay formats include label-free, quantitative, reusable, and continuous measurement capability that can be integrated with equipment-free text or image display. This Review explains the operation principles of photonic hydrogel sensors, presents syntheses of stimuli-responsive polymers, and provides an overview of qualitative and quantitative readout technologies. Applications in clinical samples are discussed, and potential future directions are identified.
Journal: Biotechnology Advances - Volume 34, Issue 3, May–June 2016, Pages 250–271