Pressure drop characteristics of cryogenic mixed refrigerant at macro and micro channel heat exchangers

► Mixed refrigerant (MR) Joule Thomson cryocooler is operated with two kinds of heat exchanger. ► Two-phase pressure drop of MR measured at macro and micro channel heat exchangers. ► Experimental data are compared with generalized two-phase pressure drop correlations. ► Cryogenic two-phase MR pressure drop can be estimated with general correlations.