کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1717169 1520029 2007 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The effect of endurance training and subsequent physical inactivity on glycaemic control after oral glucose load and physical exercise in healthy men
موضوعات مرتبط
مهندسی و علوم پایه سایر رشته های مهندسی مهندسی هوافضا
پیش نمایش صفحه اول مقاله
The effect of endurance training and subsequent physical inactivity on glycaemic control after oral glucose load and physical exercise in healthy men
چکیده انگلیسی

Physical inactivity during space flight has a profound effect on glucose metabolism. The aim of this study was to test whether endurance training (ET) may improve a negative effect of subsequent -6∘-6∘ head-down bed rest (HDBR) on glucose metabolism. Fourteen healthy males completed the study consisting of 6 weeks lasting ET followed by 6 days HDBR. Treadmill exercise at 80% of pre-training VO2maxVO2max and 75 g oral glucose tolerance test (OGTT) were performed before and after ET as well as after HDBR. ET increased VO2maxVO2max by 11%. ET significantly lowered while HDBR had no effect on fasting and OGTT plasma glucose levels. ET had no effect while HDBR was followed by an augmentation of insulin and C-peptide response to OGTT. Insulin sensitivity tended to increase after ET and to decrease during HDBR, however, mostly without statistical significance. Plasma glucose, insulin and C-peptide response to exercise were elevated after HDBR only. Our study shows that antecedent physical training could ameliorate a negative effect of simulated microgravity on insulin-mediated glucose metabolism.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Acta Astronautica - Volume 60, Issues 4–7, February–April 2007, Pages 301–306
نویسندگان
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