کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1905446 1534712 2009 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The molecular mechanism and cellular functions of mitochondrial division
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی سالمندی
پیش نمایش صفحه اول مقاله
The molecular mechanism and cellular functions of mitochondrial division
چکیده انگلیسی

Mitochondria are highly dynamic organelles that continuously divide and fuse. These dynamic processes regulate the size, shape, and distribution of the mitochondrial network. In addition, mitochondrial division and fusion play critical roles in cell physiology. This review will focus on the dynamic process of mitochondrial division, which is highly conserved from yeast to humans. We will discuss what is known about how the essential components of the division machinery function to mediate mitochondrial division and then focus on proteins that have been implicated in division but whose functions remain unclear. We will then briefly discuss the cellular functions of mitochondrial division and the problems that arise when division is disrupted.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease - Volume 1792, Issue 12, December 2009, Pages 1138–1144
نویسندگان
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