Involvement of glutathione peroxidase 1 in growth and peroxisome formation in Saccharomyces cerevisiae in oleic acid medium

► S. cerevisiae has three glutathione peroxidase homologues. ► The expression of Gpx1 was induced when cells were cultured in oleic acid medium. ► Gpx1 was present in the peroxisomal matrix. ► Deficiency in Gpx1 impaired growth and peroxisome formation in oleic acid medium. ► Redox regulation of Gpx1 is involved in peroxisome biogenesis.