
Keywords: COPD; chronic obstructive pulmonary disease; O3; ozone; BUD; budesonide; BALF; bronchoalveolar lavage fluid; MMP; matrix metalloproteinase; HIF-1α; hypoxia-inducible factor-1α; VEGF; vascular endothelial growth factor; α-SMA; α-smooth muscle actin; GS