کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1995848 1541484 2006 15 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Signalling and autophagy regulation in health, aging and disease
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Signalling and autophagy regulation in health, aging and disease
چکیده انگلیسی

It has become clear in recent years that autophagy not only serves to produce amino acids for ongoing protein synthesis and to produce substrates for energy production when cells become starved but autophagy is also able to eliminate defective cell structures and for this reason the process may be implicated in several diseased states. Autophagy is controlled by complex signalling pathways, including that used by insulin. In these pathways, phosphatidylinositol 3-kinases and the protein kinase mTOR play important roles.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Molecular Aspects of Medicine - Volume 27, Issues 5–6, October–December 2006, Pages 411–425
نویسندگان
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