Neuregulin1 administration increases axonal elongation in dissociated primary sensory neuron cultures

► We used dorsal root ganglia neuron culture as experimental model. ► We investigated the biological effects of NRG1 with particular emphasis on neurite growth. ► We tested the effects of NRG1 treatment in comparison to NGF and control conditions. ► NRG1 induces the growth of fewer but longer neurites in comparison to NGF treatment. ► The effects of NRG1 on neurite outgrowth could be partially mediated by NGF release.