کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2406398 | 1103079 | 2009 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Modeling spatial heterogeneity of disease risk and evaluation of the impact of vaccination
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موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Modeling spatial heterogeneity of disease risk and evaluation of the impact of vaccination Modeling spatial heterogeneity of disease risk and evaluation of the impact of vaccination](/preview/png/2406398.png)
چکیده انگلیسی
We reanalyzed data from a phase III trial for the killed oral cholera vaccine to test two hypotheses: there will be a greater impact of the vaccine in areas where there is a low force of infection, and the spatial pattern of disease transmission will change after a mass vaccination campaign. Spatial regression was used to test these hypotheses accounting for spatial heterogeneity in disease and vaccine coverage. The results of the analyses confirm both hypotheses. The paper also shows how spatial analysis can be used to understand the impact of vaccination when there are spatially heterogeneous disease distributions.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Vaccine - Volume 27, Issue 28, 8 June 2009, Pages 3724–3729
Journal: Vaccine - Volume 27, Issue 28, 8 June 2009, Pages 3724–3729
نویسندگان
Mohammad Ali, Michael Emch, Mohammad Yunus, John Clemens,