کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2406839 1103098 2008 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Impact and effectiveness of a mass hepatitis A vaccination programme of preadolescents seven years after introduction
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
Impact and effectiveness of a mass hepatitis A vaccination programme of preadolescents seven years after introduction
چکیده انگلیسی

SummaryAimTo investigate the impact of a mass hepatitis A vaccination programme in preadolescents seven years after introduction in terms of its effectiveness and the prevented fraction.SettingThe age distribution of notified cases and incidence rates in Catalonia (Spain) in the periods before (1992-1998) and after (1999-2005) introduction of the vaccination programme were compared.Main resultsThe incidence rates in the whole population were 5.51 per 100,000 person-years in the 1992-1998 period and 2.98 in the 1999-2005 period. The rate reduction in the 10-19 years age group was 72.43% and was more than 45% in the 5-9 years and 20-29 years age groups. The effectiveness of the vaccination programme was 99.04 (95% CI: 93.11-99.88) and the prevented fraction in the 12-19 years age group was 90.13% (95% CI: 84.47-90.89).ConclusionsThe universal vaccination programme of preadolescents has had an important impact on hepatitis A in Catalonia, not only in vaccinated cohorts but also in non-vaccinated age groups due to a herd immunity effect.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Vaccine - Volume 26, Issue 14, 25 March 2008, Pages 1737–1741
نویسندگان
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