کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2467000 1555380 2012 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Characterization of H10 subtype avian influenza viruses isolated from wild birds in South Korea
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم دامی و جانورشناسی
پیش نمایش صفحه اول مقاله
Characterization of H10 subtype avian influenza viruses isolated from wild birds in South Korea
چکیده انگلیسی

A total of 13 avian influenza viruses of the H10 subtype were isolated from wild birds in South Korea over the winter season between July 2008 and July 2011. The HA cleavage site of most of the isolated viruses, PEIMQGR↓G was similar to that of H10 viruses (A/turkey/England/384/79 and A/mandarin duck/Singapore/805/93), which are well known to be highly pathogenic in chickens. The exception was the A/mallard/Korea/1242/10(H10N6) virus, which had a PEMMQGR motif. Phylogenetic analysis showed that eight genes of the isolated H10 viruses belonged to the Eurasian lineage, and that the Korean H10 viruses could be divided four genotypes (genotypes A, B, C and D). Chicken challenge studies revealed that most of the H10 viruses did not replicate well through the natural infection route, but a genotype D virus was re-isolated from the brain of a chicken inoculated by the intravenous route. Although H10 viruses have not been isolated from poultry in South Korea, our results emphasize the continuing need to monitor the evolutionary genetics of the influenza virus in wild birds.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Veterinary Microbiology - Volume 161, Issues 1–2, 28 December 2012, Pages 222–228
نویسندگان
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