Seroprevalence of Toxoplasma gondii infection in stray and household cats in Tehran

The prevalence of anti-Toxoplasma gondii specific IgG in stray and household cats in Tehran was determined by Indirect Fluorescent Antibody Test (IFAT) on serum samples from 100 cats (50 stray and 50 households). Overall infection rate was 63%. The infection rate in stray cats (90%) was significantly higher (p < 0.001) than that of household cats (36%). Last serum positive dilutions varied from 1: 32 to 1: 512 titres in which the highest percentage (27%) was for 1:256 and the least (4.8%) was at 1:32. The rate of infection between male and female cats of both groups was not significantly different; 90.3% versus 89.5% for male and female in stray cats, respectively. Different sexes of household cats were seropositive at the same rate (36%). A high positive correlation (r2 = 0.97) between age and the rate of infection was observed. The prevalence of Toxoplasma gondii infection in cats in Tehran was high, especially in stray cats which are probably the main source of Toxoplasma infection in this area.