کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2500727 | 1556893 | 2015 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Thieno[2,3-d]pyrimidine based derivatives as kinase inhibitors and anticancer agents
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
داروسازی، سم شناسی و علوم دارویی
علوم دارویی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Thieno[2,3-d]pyrimidine based derivatives as kinase inhibitors and anticancer agents Thieno[2,3-d]pyrimidine based derivatives as kinase inhibitors and anticancer agents](/preview/png/2500727.png)
چکیده انگلیسی
Thienopyrimidines are fused heterocyclic ring systems; structurally resemble purines, exerting pharmacological potential in different aspects. They are known to play a crucial role in various disease conditions. Thieno[2,3-d]pyrimidine derivatives have been explored for their inhibitory activities towards various protein kinase enzymes. The present review is a compilation on chemical synthesis and biological anticancer significance, via inhibition of specific protein kinase enzymes, including structure–activity relationships of thieno[2,3-d]pyrimidines derivatives reported to date.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Future Journal of Pharmaceutical Sciences - Volume 1, Issue 2, December 2015, Pages 33–41
Journal: Future Journal of Pharmaceutical Sciences - Volume 1, Issue 2, December 2015, Pages 33–41
نویسندگان
Eman Z. Elrazaz, Rabah A.T. Serya, Nasser S.M. Ismail, Dalal A. Abou El Ella, Khaled A.M. Abouzid,