کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2501261 1557331 2015 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Triboelectrification of active pharmaceutical ingredients: week acids and their salts
موضوعات مرتبط
علوم پزشکی و سلامت داروسازی، سم شناسی و علوم دارویی علوم دارویی
پیش نمایش صفحه اول مقاله
Triboelectrification of active pharmaceutical ingredients: week acids and their salts
چکیده انگلیسی

The effect of salt formulation on the electrostatic property of active pharmaceutical ingredients was investigated. The electrostatic property of weak acids (carboxylic acids and amide-enole type acid) and their sodium salts was evaluated by a suction-type Faraday cage meter. Free carboxylic acids showed negative chargeability, whereas their sodium salts showed more positive chargeability than the free acids. However, no such trend was observed for amide-enole type acids.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Pharmaceutics - Volume 493, Issues 1–2, 30 September 2015, Pages 434–438
نویسندگان
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