کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2502421 | 1557383 | 2013 | 18 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Polyurethane-based drug delivery systems
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
داروسازی، سم شناسی و علوم دارویی
علوم دارویی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Polyurethanes (PUs) are formed by a reaction between isocyanates and diols to yield polymers with urethane bonds (–NH–COO–) in their main chain. A great variety of building blocks is commercially available that allows the chemical and physical properties of PUs to be tailored to their target applications, particularly for the biomedical and pharmaceutical fields. This article reviews the synthesis and characterization of PUs and PU-copolymers, as well as their in vitro and in vivo biodegradability and biocompatibility. Particular emphasis is placed on the use of PUs for the controlled release of drugs and for the (targeted) delivery of biotherapeutics.
Figure optionsDownload high-quality image (222 K)Download as PowerPoint slide
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Pharmaceutics - Volume 450, Issues 1–2, 25 June 2013, Pages 145–162
Journal: International Journal of Pharmaceutics - Volume 450, Issues 1–2, 25 June 2013, Pages 145–162
نویسندگان
Jong Yuh Cherng, Ting Yi Hou, Mei Fen Shih, Herre Talsma, Wim E. Hennink,