کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2510811 | 1117986 | 2009 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Anti-hepatitis B virus activity of chlorogenic acid, quinic acid and caffeic acid in vivo and in vitro
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
DHBV, duck hepatitis B virusHBeAg, hepatitis B e antigen - HBeAg، آنتی ژن هپاتیت BHBsAg, Hepatitis B virus surface antigen - HBsAg، آنتیژن سطح ویروسی هپاتیت BHSV, herpes simplex virus - HSV، ویروس هرپس سیمپلکسHIV, human immunodeficiency virus - ویروس نقص ایمنی انسانیHBV, Hepatitis B virus - ویروس هپاتیت بی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ویروس شناسی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Anti-hepatitis B virus activity of chlorogenic acid, quinic acid and caffeic acid in vivo and in vitro Anti-hepatitis B virus activity of chlorogenic acid, quinic acid and caffeic acid in vivo and in vitro](/preview/png/2510811.png)
چکیده انگلیسی
Chlorogenic acid and its related compounds are abundant plant polyphenols that have a diverse antiviral activity. In this study, HepG2.2.15 cells and duck hepatitis B virus infection model were used as in vitro and in vivo models to evaluate their anti-HBV activity. In the cell model, all the three compounds inhibited HBV-DNA replication as well as HBsAg production. Chlorogenic acid and caffeic acid also reduced serum DHBV level in DHBV-infected duckling model. Moreover, the anti-HBV activity of crude extracts of coffee beans, which have a high content of chlorogenic acid, was studied. Both the extracts of regular coffee and that of decaffeinated coffee showed inhibitory effect on HBV replication.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Antiviral Research - Volume 83, Issue 2, August 2009, Pages 186–190
Journal: Antiviral Research - Volume 83, Issue 2, August 2009, Pages 186–190
نویسندگان
Gui-Feng Wang, Li-Ping Shi, Yu-Dan Ren, Qun-Fang Liu, Hou-Fu Liu, Ru-Jun Zhang, Zhuang Li, Feng-Hua Zhu, Pei-Lan He, Wei Tang, Pei-Zhen Tao, Chuan Li, Wei-Min Zhao, Jian-Ping Zuo,