کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
25338 43568 2006 14 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Advances in cloning, functional analysis and heterologous expression of fungal polyketide synthase genes
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی بیو مهندسی (مهندسی زیستی)
پیش نمایش صفحه اول مقاله
Advances in cloning, functional analysis and heterologous expression of fungal polyketide synthase genes
چکیده انگلیسی

Fungal polyketides comprise a diverse group of secondary metabolites that play an important role for drug discovery, as pigments, and as mycotoxins. Their biosynthesis is governed by multidomain enzymes, so-called fungal type I polyketide synthases (PKS). Investigating the molecular basis of polyketide biosynthesis in fungi is of great importance for ecological and pharmacological reasons. In addition, cloning, functional analysis and expression of fungal PKS genes also set the basis for engineering the yet largely untapped biosynthetic potential.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Biotechnology - Volume 124, Issue 4, 5 August 2006, Pages 690–703
نویسندگان
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