کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2566233 1128077 2006 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Perospirone in the treatment of schizophrenia: Effect on verbal memory organization
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی روانپزشکی بیولوژیکی
پیش نمایش صفحه اول مقاله
Perospirone in the treatment of schizophrenia: Effect on verbal memory organization
چکیده انگلیسی
The present study was performed to determine if perospirone, a novel antipsychotic drug with D2/5-HT2A antagonist and partial 5-HT1A agonist properties, would improve memory organization in twelve patients with chronic schizophrenia. Switching to equivalent dose of perospirone from prior antipsychotic medication was associated with a significant improvement in indices of verbal memory organization of the Auditory Verbal Learning Test. Negative symptoms and extrapyramidal side effects were also ameliorated after switching to perospirone. The distinct cognitive enhancement profile of perospirone may be attributable to its partial 5-HT1A agonist action.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Progress in Neuro-Psychopharmacology and Biological Psychiatry - Volume 30, Issue 2, March 2006, Pages 204-208
نویسندگان
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