کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2566481 1128084 2006 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Glial fibrillary acidic protein expression after electroconvulsive shocks in rat brain
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی روانپزشکی بیولوژیکی
پیش نمایش صفحه اول مقاله
Glial fibrillary acidic protein expression after electroconvulsive shocks in rat brain
چکیده انگلیسی

ObjectiveThe aim of the present study was to assess the effect of electroconvulsive shock (ECS) in glial fibrillary acidic protein (GFAP) expression in rat brain.MethodsRats were given either a single (acute) or a series of eight (chronic) ECS. Brain regions were isolated and levels of glial fibrillary acidic protein (GFAP) in the brain tissue (cortex, hippocampus, and cerebellum) were assessed using an enzyme-linked immunosorbent assay (ELISA).ResultsWe showed that GFAP expression is reduced in the hippocampus within 48 h and 7 days after acute ECS. GFAP levels are increased in the cerebellum immediately after acute and chronic ECS. No changes were observed in the cortex.ConclusionsOur findings showed a differential effect of acute and chronic ECS in the astroglial response in the brain of rats.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Progress in Neuro-Psychopharmacology and Biological Psychiatry - Volume 30, Issue 4, June 2006, Pages 663–667
نویسندگان
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