کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2566645 | 1128088 | 2006 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Adjunctive risperidone, olanzapine and quetiapine for the treatment of hospitalized patients with bipolar I disorder: A retrospective study
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کلمات کلیدی
EPSExtrapyramidal symptomrCGDSM-IVGAFYMRSOCGCGIBipolar I disorder - اختلال Bipolar IGlobal Assessment of Functioning - ارزیابی جهانی عملکردOlanzapine - الانزاپینInpatients - بیماران بستریANOVA - تحلیل واریانس Analysis of varianceTardive dyskinesia - دیسکینزی خفیفDiagnostic and Statistical Manual of Mental Disorders, fourth edition - راهنمای تشخیصی و آماری اختلالات روانی، نسخه چهارمRisperidone - ریسپریدون Naturalistic study - مطالعه طبیعت گرایانهHamilton Depression Rating Scale - مقیاس رتبه بندی افسردگی همیلتونHAMD - همدنClinical Global Impression - چشم انداز جهانی بالینیQuetiapine - کواتیاپین
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
روانپزشکی بیولوژیکی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
This study evaluated the overall effectiveness and tolerability of atypical antipsychotics (risperidone vs. olanzapine vs. quetiapine) used in the treatment of bipolar inpatients. After screening 463 patients, the medical records of 158 inpatients with bipolar I disorder, who were given olanzapine, risperidone or quetiapine as adjuncts to mood stabilizers for at least 1Â month and not administered with any other antipsychotics, were examined. Details of the tolerability and effectiveness were reviewed according to the treatment records during their hospital stay. The results showed equivalent effectiveness based on the Clinical Global Impression (CGI) and Global Assessment Functioning (GAF) score between the three atypical antipsychotics. The frequency of the extrapyramidal symptom-related side effects were higher in the risperidone-treated group than in the olanzapine and quetiapine-treated group. This suggests that risperidone, olanzapine and quetiapine have a comparable effectiveness in inpatients with bipolar I disorder in a naturalistic setting. However, there were some differences in tolerability between these results as reported from previous Western studies.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Progress in Neuro-Psychopharmacology and Biological Psychiatry - Volume 30, Issue 7, 30 September 2006, Pages 1322-1325
Journal: Progress in Neuro-Psychopharmacology and Biological Psychiatry - Volume 30, Issue 7, 30 September 2006, Pages 1322-1325
نویسندگان
Chi-Un Pae, S. Nassir Ghaemi, Ashwin Patkar, Jeong-Ho Chae, Won-Myong Bahk, Tae-Youn Jun, Prakash Masand,