Propoxyphene use and risk for hip fractures in older adults

The results of this cohort database study suggest that propoxyphene use among adults aged ≥65 years is associated with increased risk for hip fracture and suggest a need for interventions to reduce propoxyphene use in older adults. Clinicians should be aware of the risk for hip fracture with other opioids as well and weigh them against potential benefits when prescribing for older adults.