کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2820772 1160890 2013 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Database tools in genetic diseases research
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی ژنتیک
پیش نمایش صفحه اول مقاله
Database tools in genetic diseases research
چکیده انگلیسی

The knowledge of the human genome is in continuous progression: a large number of databases have been developed to make meaningful connections among worldwide scientific discoveries. This paper reviews bioinformatics resources and database tools specialized in disseminating information regarding genetic disorders. The databases described are useful for managing sample sequences, gene expression and post-transcriptional regulation. In relation to data sets available from genome-wide association studies, we describe databases that could be the starting point for developing studies in the field of complex diseases, particularly those in which the causal genes are difficult to identify.


► Database tools for studying monogenic and complex genetic disease.
► Genomic browser allows association between disease phenotype and genetic loci.
► IBD analysis with bioinformatics tools.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Genomics - Volume 101, Issue 2, February 2013, Pages 75–85
نویسندگان
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