کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2869455 | 1171247 | 2008 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Intérêt des statines dans la prévention des infarctus postangioplastie coronaire : revue systématique et méta-analyse
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Intérêt des statines dans la prévention des infarctus postangioplastie coronaire : revue systématique et méta-analyse Intérêt des statines dans la prévention des infarctus postangioplastie coronaire : revue systématique et méta-analyse](/preview/png/2869455.png)
چکیده انگلیسی
Postprocedural myocardial necrosis as indicated by biomarkers increase is frequent after percutaneous coronary interventions (PCI) in up to 40% of cases. Pretreatment by statin could reduce the occurrence of those periprocedural myonecrosis. Medline and Cochrane Database screenings allow us to select articles published until March 2007. Sixteen prospective and retrospective studies have been identified in relation with the impact of statin pretreatment on periprocedural myonecrosis or morbimortality outcomes in patients who underwent PCI. Among selected studies, 12 provide the rate of periprocedural myocardial infarction. The relative risk (RR) of periprocedural myocardial necrosis in patients pretreated with statin was 0.50 (95% CI: 0.40-0.63). Among the 5409 patients with clinical follow-up ensured until six months, the RR of death in patients pretreated with statin before the PCI was 0.64 (95% CI: 0.44-0.93). Significant heterogeneity was observed in the results. In sensitivity analysis, stable and unstable patients were compared with similar RR reduction of periprocedural myonecrosis in favour of patients receiving statin before PCI. In the present meta-analysis, we confirm that statin pretreatment before PCI is able to reduce periprocedural myonecrosis and suggest a potential impact on six months survival of patients.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Annales de Cardiologie et d'Angéiologie - Volume 57, Issue 3, June 2008, Pages 181-186
Journal: Annales de Cardiologie et d'Angéiologie - Volume 57, Issue 3, June 2008, Pages 181-186
نویسندگان
Marie-Rose Clergeau, Rémy Morello, Olivier Lepage, Martial Hamon,