کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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2938789 | 1176957 | 2009 | 10 صفحه PDF | دانلود رایگان |

ObjectivesWe evaluated the usefulness of the ratio of the early diastolic transmitral flow velocity (E) to the mitral annular velocity (e′) calculated from simultaneously recorded E and e′ in atrial fibrillation (AF).BackgroundThe ratio of the E to the e′ (E/e′) has been reported as a useful index even in AF patients. However, E and e′ were measured during different beats in the previous studies.MethodsFifty-six AF patients with preserved systolic function (mean age 66 ± 11 years) underwent routine echocardiographic study. The E/e′ was calculated from the E and e′ simultaneously recorded by the dual Doppler echocardiography. A single-beat E/e′ was calculated from simultaneously recorded E and e′ when the preceding RR interval/pre-preceding RR interval = 1. Brain natriuretic peptide (BNP) levels were also examined. Twenty-one patients underwent simultaneous pulmonary artery catheterization.ResultsThe single-beat lateral E/e′ correlated with pulmonary capillary wedge pressure (PCWP) (r = 0.74, p < 0.001). The single-beat lateral E/e′ of ≥11 could predict elevated PCWP (≥15 mm Hg) with a sensitivity of 90% and a specificity of 90%. The single-beat lateral E/e′ also correlated well with the log BNP concentration. The single-beat lateral E/e′ of ≥9.2 predicted a plasma BNP level of ≥200 pg/ml with 88% sensitivity and 84% specificity.ConclusionsThe single-beat lateral E/e′ correlated with plasma BNP level and PCWP in AF patients with preserved systolic function. In addition, the single-beat lateral E/e′ (≥11) was a good predictor of elevated PCWP (≥15 mm Hg). Dual Doppler echocardiography offers an advantage of providing the single-beat lateral E/e′ correctly even in AF patients, for the evaluation of left ventricular diastolic function.
Journal: JACC: Cardiovascular Imaging - Volume 2, Issue 10, October 2009, Pages 1147–1156