Role of Left Ventricular Twist Mechanics in the Assessment of Cardiac Dyssynchrony in Heart Failure

The authors discuss an incremental value of assessing left ventricular (LV) twist mechanics in patients with heart failure (HF) and its potential usefulness in characterizing response to cardiac resynchronization therapy (CRT) and reversal of LV remodeling at 6 months follow-up. They also underscore a critical relationship between LV lead position and changes in LV twist after CRT, and suggest that the reversal of LV remodeling in HF patients following CRT primarily results from restoration of the global sequence of LV twist mechanics.