Are Depressive Symptoms Associated with Cardiovascular Mortality Among Older Chinese: A Cohort Study of 64,000 People in Hong Kong?

Depressive symptoms were independently associated with higher CHD mortality in older Chinese men, and with higher stroke mortality in both genders. However, attenuation by health status, and lack of consistency by gender indicate that these associations could be noncausal and further studies by treatment trials and Mendelian randomization are needed.