Prevention of Late-Life Anxiety and Depression Has Sustained Effects Over 24 Months: A Pragmatic Randomized Trial

A stepped-care approach to the prevention of depression and anxiety in late life was not only successful in halving the incidence of depressive and anxiety disorders after 1 year, but these favorable effects were also sustained over 24 months. (Am J Geriatr Psychiatry 2011; 19:230-239)