کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3036063 | 1579627 | 2014 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Mild cognitive impairment in Parkinson's disease: How much testing is needed for correct diagnosis?
ترجمه فارسی عنوان
اختلال شناختی خفیف در بیماری پارکینسون: چقدر آزمایش برای تشخیص صحیح لازم است؟
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کلمات کلیدی
بیماری پارکینسون، اختلال شناختی خفیف، نوروپسیکتیک، شناختی روان سنجی، کم خونی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
عصب شناسی
چکیده انگلیسی
Cognitive deficits are one of the most common non-motor symptoms of Parkinson's disease (PD). Mild cognitive impairment (MCI) affects about 27% of non-demented PD patients. The high prevalence of PD-MCI and PD with dementia (PD-D) as well as increasing life expectancy in PD creates the need for valid serial cognitive assessment in every PD clinic. In this paper we discuss the PD-MCI criteria and testing recommendations (Movement Disorder Society Task Force Guidelines) in the context of referral for neuropsychological assessment in clinical practice. The methodology suggested in the PD-MCI diagnosis guidelines is compared against PD-D testing recommendations. The requirement for at least 10 cognitive tests to allow PD-MCI subtype to be determined is questioned, as a direct correspondence between low scores on a particular test and a domain-specific deficit cannot be assumed. As a variety of factors may underlie an impaired test score, the same test score may be affected by different deficits in different patients (e.g. a low verbal fluency score may be due to executive or language decline). A pathway approach to PD-MCI diagnosis is presented, inline with PD-D diagnostic guidelines. In cases where thorough screening results and clinical history are consistent with each other and presentation seems typical for PD-MCI, level I diagnosis could be established without neuropsychological assessment. However, when screening results diverge from the clinical history or the presentation is atypical, neuropsychological assessment should precede the diagnostic formulation.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Basal Ganglia - Volume 4, Issues 3â4, December 2014, Pages 89-94
Journal: Basal Ganglia - Volume 4, Issues 3â4, December 2014, Pages 89-94
نویسندگان
Emilia J. Sitek, JarosÅaw SÅawek, Jonathan J. Evans,