کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3056851 1186578 2008 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Inflammation and its role in neuroprotection, axonal regeneration and functional recovery after spinal cord injury
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی عصب شناسی
پیش نمایش صفحه اول مقاله
Inflammation and its role in neuroprotection, axonal regeneration and functional recovery after spinal cord injury
چکیده انگلیسی

Trauma to the central nervous system (CNS) triggers intraparenchymal inflammation and activation of systemic immunity with the capacity to exacerbate neuropathology and stimulate mechanisms of tissue repair. Despite our incomplete understanding of the mechanisms that control these divergent functions, immune-based therapies are becoming a therapeutic focus. This review will address the complexities and controversies of post-traumatic neuroinflammation, particularly in spinal cord. In addition, current therapies designed to target neuroinflammatory cascades will be discussed.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Experimental Neurology - Volume 209, Issue 2, February 2008, Pages 378–388
نویسندگان
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