Restriction de sommeil et risque cardiovasculaire

Our 24 h society promotes wakefulness to the detriment of sleep. Many people reduce their sleep time voluntary or by obligation. The effects of sleep restriction on performances and on vigilance are becoming to be recognized. However, the effects of chronic sleep loss on health and disease, particularly cardiovascular disease, are less documented. Several studies have evidenced a relation between a reduction of sleep duration and cardiovascular pathology. The mechanisms involved in these associations are not elucidated at the present time. We are using the sleep restriction model in order to evaluate the relationships between sleep reduction and the inflammatory processes involved in cardiovascular diseases. Our data show that a sleep restriction, even moderated, is able to influence cardiovascular risk factors in otherwise healthy subjects.