کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3069123 1188268 2008 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Les comportements oniriques chez le patient parkinsonien
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی مغز و اعصاب بالینی
پیش نمایش صفحه اول مقاله
Les comportements oniriques chez le patient parkinsonien
چکیده انگلیسی
REM sleep behaviour disorders (RBD) are vigorous, complex movements corresponding to enacted dreams. They may disturb sleep, and injure the patients or their bed partner. RBD are frequently associated with neurodegenerative diseases, especially synucleopathies. They can precede parkinsonism or dementia for 5 to 10 years, co occur, or follow parkinsonism and dementia for few years.The presymptomatic RBD are frequently associated with EEG slowing, reduced olfaction, mild visuo-spatial cognitive impairment, and decreased dopamine transport in functional brain imaging. In Parkinson's disease, 15 to 59 % patients speak, laugh, shout, kick, punch or fight invisible enemies during REM sleep. In contrast to sleepwalkers, patients with RBD rarely stand up or walk, but can fall out their bed. Sleep monitoring indicates an imperfect abolition of muscle tone during REM sleep in these patients. RBD are probably caused by non-dopaminergic pontine lesions in the REM sleep atonia system. This condition may also expose patients with Parkinson's disease to a higher risk of daytime and night-time hallucinations. Interestingly, several spouses reported that they observed a sharp contrast between the slow, limited movements, and poorly intelligible, low voice of their affected spouse when awake, and the fast, vigorous movements with loud voice that the very same patient exhibited during enacted dreams. We recently demonstrated,in a large study combining the interview of 100 couples and the sleep and video monitoring of 50 patients, that parkinsonism indeed disappears during RBD. The mechanism of this improvement is now explored.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Médecine du Sommeil - Volume 5, Issue 15, March 2008, Pages 16-22
نویسندگان
, ,