Análisis de la presencia de mutaciones por pérdida de heterocigocidad de 1p/19q en tumores cerebrales de estirpe glial

Evaluation of 1p/19q allelic status by LOH analysis may provide useful information for guiding clinical and therapeutical decisions with high succes ratio. These results shown why patients with 1p/19q codeletion survive longer, because adjuvant alkylants adds further improvements to standard, surgery and radiotherapy, treatments.