کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
30770 | 44502 | 2011 | 9 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Synthesis and evaluation of novel tetrapropoxycalix[4]arene enones and cinnamates for protection from ultraviolet radiation Synthesis and evaluation of novel tetrapropoxycalix[4]arene enones and cinnamates for protection from ultraviolet radiation](/preview/png/30770.png)
A series of novel calix[4]arene enones (5–7) and cinnamates (12–14) have been synthesized and evaluated for ensuring protection from ultraviolet radiation (UVR). Spectroscopic analyses has revealed that compound 6 absorbs ultraviolet radiations between 280 and 350 nm with an absorption maximum at 312 nm. Its molar absorption coefficient (ε) (>5 × 104 M−1 cm−1) and bandwidth are larger than those for the commercially used sun protectants (oxybenzone (OB), 2-ethylhexyl 4-methoxycinnamate (OMC) and avobenzone). The in vitro Sun Protection Factor (SPF) measurement revealed an SPF of 5.2 at 2% concentration of 6 in home made emulsion formulations while combination of 2% each of 6 and OMC gave an SPF of 8.8. Lower sun protection seems to be compensated by significant protection from more harmful UVA radiations (UVA/UVB absorbance ratio of 0.62).
Potential of using substituted calix[4]arene enones for sun protection has been investigated.Figure optionsDownload as PowerPoint slideHighlights
► Functionalized calixarenes can function as useful UV-A and UV-B sun protectants.
► Rapid conformational isomerization of calixarenes can be deployed for better dissipation of absorbed energy.
► Formulations developed from calixarenes function analogous to currently used UVA protectant, avobenzone.
► Synergistic action of calixarenes and octylmethoxycinnamate (OMC) in Sun Protection Factor (SPF) analysis has been observed.
Journal: Journal of Photochemistry and Photobiology B: Biology - Volume 105, Issue 1, 5 October 2011, Pages 25–33