کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
30781 | 44502 | 2011 | 7 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: A mathematical model for seasonal variability of vitamin D due to solar radiation A mathematical model for seasonal variability of vitamin D due to solar radiation](/preview/png/30781.png)
It is widely recognized that vitamin D deficiency has detrimental health consequences. The ultraviolet (UV) B radiation increases the serum vitamin D level, expressed by 25-hydroxyvitamin-D3 [25(OH)D]. An analytical model is presented to calculate the serum 25(OH)D changes throughout a year, caused by the solar exposure variability due to geophysical and habitual factors. The model is tuned by taking into account recent experimental results of serum 25(OH)D changes, after a series of artificial (by fluorescent tubes) UV exposures. The model uses the erythemal and vitamin D weighted irradiances, inferred from the Brewer spectrophotometer and the Kipp and Zonen broad-band meter measurements, carried out in Belsk (52°N, 21°E), Poland, in 2010. The modeled seasonal pattern of the serum 25(OH)D concentration in Polish indoor workers is only slightly different, than in subjects with typical outdoor activity habits, and in those with sun-seeking behavior. A deep minimum in the serum 25(OH)D concentration appears in late winter, regardless of outdoor activity habits. An extra sunbathing to boost the vitamin D level is not worth taking, because of a minor improvement of the vitamin D status, and because of a greater erythema risk. It would be much safer and more effective to maintain an adequate vitamin D level through diet supplements, even in summer, for non sun-seeking subjects.
► A model of outdoor UV exposure impact on vitamin D status in humans is developed.
► Model input is based on the irradiance observations and possible outdoor scenarios.
► Vitamin D status throughout 2010 is calculated for typical Polish indoor workers.
► The workers could not maintain adequate vitamin D level throughout most of the year.
► Boosting vitamin D level by sunbathing is risky (erythema) and not much help solution.
Journal: Journal of Photochemistry and Photobiology B: Biology - Volume 105, Issue 1, 5 October 2011, Pages 106–112