Influence des poussées sur la survenue d'un handicap au long cours dans la sclérose en plaques de forme rémittente : étude observationnelle de 99 patients

In spite of a limited number of patients, this study gives evidence that a high rate of acute exacerbations in RR-MS patients after the second clinical event may be an independent predictive factor of long-term residual disability progression. High relapse rate leads to a more frequent and faster SP or EDSS>4.0 occurrence.