کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3121136 1583382 2008 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Interplay of mechanical loading and growth factors in the mandibular condyle
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی دندانپزشکی، جراحی دهان و پزشکی
پیش نمایش صفحه اول مقاله
Interplay of mechanical loading and growth factors in the mandibular condyle
چکیده انگلیسی

The mandibular condyle is an important growth site in the developing mandible. The growth of the condyle is known to be highly adaptable to functional factors. This property is exploited in orthodontics for the treatment of class II malocclusions and mandibular asymmetries. However, there is an ongoing debate on the efficacy of functional appliances. The comparison of experimental studies is complicated by the lack of detailed analyses of the load distribution within the condyle. In spite of this, there is a large body of evidence showing that mechanical manipulation of the condyle induces metabolic changes, and changes in the expression of growth factors and other signalling molecules. This review aims to give an overview of the role of growth factors in the condyle with special emphasis on their responsiveness to mechanical perturbation.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Archives of Oral Biology - Volume 53, Issue 8, August 2008, Pages 709–715
نویسندگان
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