کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3136381 1584968 2016 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Evidence-based recommendations for antibiotic usage to treat endodontic infections and pain : A systematic review of randomized controlled trials
ترجمه فارسی عنوان
توصیه های مبتنی بر شواهد برای استفاده از آنتی بیوتیک برای درمان عفونت های اندودنتیتیک و درد: بررسی سیستماتیک از آزمایشات تصادفی کنترل شده
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی دندانپزشکی، جراحی دهان و پزشکی
چکیده انگلیسی

BackgroundThe purpose of this investigation was to identify evidence-based scientific methodologies to aid dental clinicians in establishing the indications for prescribing antibiotics for endodontic infection or pain.MethodsThe authors prepared and registered a protocol on PROSPERO. They conducted electronic searches in MEDLINE, Scopus, Cochrane Library, and ClinicalTrials.gov. In addition, the authors hand searched the bibliographies of all relevant articles, the gray literature, and textbooks for randomized controlled clinical studies. The authors independently selected the relevant articles.ResultsThe overall quality of the studies was fair with a low risk of bias, but 2 studies had a moderate risk of bias.ConclusionsThe best available clinical evidence signals no indications for prescribing antibiotics preoperatively or postoperatively to prevent endodontic infection or pain unless the spread of infection is systemic, the patient is febrile, or both. Generally, an accurate diagnosis coupled with effective endodontic treatment will decrease microbial flora enough for healing to occur.Practical ImplicationsTo help decrease the number of drug-resistant microbes, oral health care providers should not prescribe antibiotics when they are not indicated.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Journal of the American Dental Association - Volume 147, Issue 3, March 2016, Pages 186–191
نویسندگان
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